Pharmacovigilance · Drug Safety · Life Sciences IT

Where Drug Safety Meets Operational Excellence

Gateway Safety Solutions delivers senior-level pharmacovigilance consulting at the intersection of clinical expertise, regulatory compliance, and enterprise technology — including AI/ML integration into PV workflows.

Credentials & Track Record
20+
Years in PV & Pharma IT
PharmD
Clinical Foundation, STLCOP '94
21 CFR
Part 11 & GxP Validation
AI/ML
PV Automation & Integration
PV Safety SystemsE2B(R2/R3) ICSR ProcessingFDA / EMA EudraVigilanceGxP / CSV
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Dual Expertise
Rare combination of PharmD clinical credentials and enterprise IT systems depth
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AI/ML Integration
Proven implementation of AI-powered ICSR intake and adverse event automation
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GxP Validated
Comprehensive 21 CFR Part 11 compliance, CSV, and regulatory audit support
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St. Louis Based
Serving pharma clients globally, remote-capable, with deep US and EU regulatory expertise
What Clients Say

Client Testimonials

Verified LinkedIn recommendations from colleagues, clients, and technology partners

★★★★★
"

Paul and I worked together on pharmacovigilance digital implementation projects for several years. I was the Client PM and he was the SaaS Provider PM & Business Analyst. I had confidence in his deliverables because of his ability to dig into complexity, figure out the details, understand the big picture, think from the user's perspective, and communicate well with management. Paul would be a great asset to lead or participate with any team.

JA
Janet
Digital Solution Delivery Project Manager
LinkedIn Recommendation · 2025
★★★★★
"

Paul brings a wide array of skills to the table. He's an exceptional communicator with a real talent for engaging clients and navigating complex requirements. What truly sets Paul apart is his ability to connect with stakeholders across all levels — from C-suite executives to technical analysts — moving seamlessly between strategic and technical discussions on both the pharmacovigilance and IT sides. His versatility and confidence in these moments are rare and deeply valued. Paul is reliable, insightful, and a true partner. If you're lucky enough to work with him, take it.

WL
Will
Head of Product Development
LinkedIn Recommendation · 2025
★★★★★
"

Paul was instrumental in the migration of safety adverse event data. He led the partner effort in ensuring the data present in the safety database was in acceptable format and with high quality to ensure a smooth transition of critical safety data. His many years of experience with Oracle safety databases gave the team confidence that both migration teams were speaking the same requirements. I have no hesitation in recommending Paul for your Safety Database migrations.

AN
Andrew
Director, Patient Safety Due Diligence & Alliance Management
LinkedIn Recommendation · 2025
★★★★★
"

Paul is an absolute pleasure to work with. Among his many talents is his unique skill of being able to translate complex technology details and requirements into simple, practical language — making him a huge asset on any implementation project and a fantastic Project Manager. He is well organized and an incredibly hard worker, quickly forging meaningful and lasting relationships with colleagues and clients alike. A real asset to any company he chooses to work for.

WF
Wilfred
Vice President, Head of US Practice
LinkedIn Recommendation · 2025
★★★★★
"

Paul was a tremendous asset in client conversations explaining how AI worked within the pharma industry. His knowledge base was incredible — any question the leadership team had on the pharma subject was easily answered. Paul was instrumental in guiding the AI models in the right directions. I remember when our deep learning algorithms kept flagging a 20-digit number as a strong feature. Paul quickly determined what those numbers meant and showed us how the data was biasing results — allowing us to fix the models. Without Paul, these models would not have survived in production.

DV
David
Machine Learning Engineer
LinkedIn Recommendation · 2020 · AI Pharmacovigilance Platform
★★★★★
"

I have had the privilege to work with Paul over the years. Paul is an excellent communicator that succeeds in anything he is chartered to do. He is equally comfortable working for pharma and industry as well as a service provider within the PV space. He has a keen awareness of the possibilities and opportunities for AI to revolutionize and automate the day-to-day Drug Safety workplace. His character, personality, and work ethic are above reproach — he takes pride and great care to be the best he can be. I look forward to working with Paul again and highly endorse him based on my experiences across multiple successful projects where he was instrumental in ensuring the desired outcomes were met.

RL
Raul
Director of Project Delivery
LinkedIn Recommendation · 2020
PAR
Paul A. Reed, PharmD, BS MIS
Pharmacovigilance Consultant · Principal at Gateway Safety Solutions, LLC
PV Safety Systems · GxP Validation · AI/ML · St. Louis, MO
500+
Connections
20+
Years Exp.
4
Companies
PharmacovigilancePV Safety Systems GxP ValidationAI/ML PV E2B(R2/R3)21 CFR Part 11 Drug SafetyLife Sciences IT
Connect on LinkedIn

Ready to Elevate Your Drug Safety Program?

Whether you need Argus configuration, GxP validation, or AI/ML implementation — let's talk.

🛡️

PV System Implementation

Expert configuration, validation, and optimization of enterprise drug safety platforms across all major vendors.

  • Safety system implementation, upgrade & migration
  • Safety database configuration & workflow design
  • Data migration, mapping & reconciliation
  • System integration (E2B, MedWatch, WHO, EudraVigilance)
  • UAT design, execution & sign-off
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GxP Validation & Compliance

Comprehensive 21 CFR Part 11 compliant validation programs for safety-critical systems.

  • Computer System Validation (CSV/CSA)
  • IQ / OQ / PQ protocol authoring
  • Validation master plans & traceability matrices
  • SOP development and training materials
  • FDA inspection readiness support
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AI/ML in Pharmacovigilance

Next-generation automation for ICSR intake, signal detection, and PV workflow optimization.

  • AI-powered adverse event intake automation
  • NLP-based case triage and routing
  • ML model validation for regulatory use
  • Integration architecture design
  • AI governance & audit trail requirements
  • AI training, change management & user adoption
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PV Operations & Outsourcing

Operational support for safety departments navigating resource constraints or scaling challenges.

  • ICSR processing & case management
  • Business process redesign for PV operations
  • M&A safety system transitions & data divestment
  • Vendor oversight and audit support
  • PV department buildout consulting
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Regulatory Strategy & Submissions

Strategic guidance on global safety reporting requirements and regulatory compliance frameworks.

  • ICH E2B(R2) & E2B(R3) compliance & submissions
  • EudraVigilance & global regulatory gateway submissions
  • EU GVP Module compliance & implementation
  • Regulatory inspection readiness & CAPA management
  • Safety Management Team support & advisory
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Training & Education

Custom training programs for PV teams, safety system users, and cross-functional stakeholders.

  • Safety system end-user training
  • GxP and regulatory fundamentals
  • AI/ML literacy for drug safety teams
  • SOP-based training module development
  • On-site or virtual delivery
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Project & Program Management

End-to-end project leadership for drug safety technology initiatives — from planning through go-live and beyond.

  • Full lifecycle PV system implementation management
  • SaaS upgrade & platform transition oversight
  • Budget management & stakeholder engagement
  • RFP authoring, contract & vendor negotiation
  • Go-live support & post-implementation optimization
  • Microsoft Project, Smartsheet, JIRA & Monday.com
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Global Consulting Network

Access to a vetted international network of pharmacovigilance and life sciences technology specialists.

  • Global experts across all major safety database platforms
  • Specialists in cloud, SaaS & on-premise hosting solutions
  • EU, US & APAC regulatory affairs consultants
  • Data migration & integration architects
  • GxP validation & quality assurance professionals
  • Scalable resourcing for large-scale implementations

Not Sure Which Service You Need?

A discovery call is the fastest way to scope your project and get a tailored proposal.

Safety System Implementation

Deep expertise across all major enterprise pharmacovigilance platforms — from fresh installs and SaaS upgrades to complex multi-system integrations, data migrations, and M&A transitions.

Safety Database Configuration

Configuration, validation, and optimization of industry-leading safety databases, including ICSR workflow design, regulatory submission pipelines, and reporting architecture.

21 CFR Part 11 / GxP

Comprehensive computer system validation including IQ/OQ/PQ protocols, audit trails, electronic records/signatures, Annex 11 compliance, and FDA inspection preparedness.

AI/ML in PV

Delivered client implementations of an AI-powered adverse event intake platform through Gateway Safety Solutions. Direct experience with NLP, case triage automation, user adoption programs, and safety system API integration.

Regulatory Frameworks

EudraVigilance, ICH E2B(R2) & E2B(R3), EU GVP Modules, MedDRA coding, and global ICSR reporting requirements across US and EU regulatory jurisdictions.

Project & Program Management

End-to-end program leadership for PV technology initiatives — budgets, stakeholders, RFPs, vendor negotiations, go-live support, and post-implementation optimization across global engagements.

Platform & Technology Proficiency

PV Safety System ImplementationExpert
GxP / CSV / 21 CFR Part 11Expert
ICH E2B(R2/R3) / FDA / EMA RegulationsExpert
ICSR Processing & Case ManagementExpert
Project & Program ManagementExpert
AI/ML PV IntegrationAdvanced

Ready to Put This Expertise to Work?

Let's discuss your PV program and how Gateway Safety Solutions can help.

A Rare Combination of Clinical Depth and Systems Expertise

Gateway Safety Solutions was founded on a simple premise: the most effective pharmacovigilance consulting comes from someone who has operated at both ends of the spectrum — as a trained clinical pharmacist who understands drug safety from the ground up, and as an enterprise IT professional who has built, validated, and optimized the systems that power global safety programs.

Dr. Paul A. Reed brings over two decades of experience spanning traditional Big Pharma, global CRO environments, and cutting-edge AI/ML startups. That breadth translates into solutions that are clinically sound, technically rigorous, and operationally practical.

Based in St. Louis, Missouri, Gateway Safety Solutions serves clients across the pharmaceutical, biotech, and life sciences sectors — delivering contract and FTE-adjacent consulting engagements remotely and on-site.

🏛️
2014 – Present
Gateway Safety Solutions, LLC
Independent consulting practice specializing in PV systems, GxP validation, and AI/ML integration — available for contract and FTE opportunities, remote or St. Louis-area.
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Recent
AI-Powered PV — Head of Client Delivery
Engaged through Gateway Safety Solutions to lead enterprise client implementations of an NLP-powered adverse event intake platform, deploying solutions that integrated with safety databases in under 60 seconds per case.
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Mid-Career
Nextrove & Genpact
Expanded into PV consulting and global CRO environments, leading system implementations and validation programs for multi-national pharmaceutical clients.
🏥
2002 – 2016
Forest Laboratories / Allergan
14-year tenure across drug safety operations, building deep expertise in ICSR processing, aggregate reporting, and safety system management through the Allergan acquisition era.
President & Founder
Dr. Paul A. Reed
President & Founder
PharmD · STLCOP, 1994
BS MIS · Maryville University
RPh · Missouri & Illinois
Connect

Dr. Paul A. Reed, PharmD, BS MIS

Dr. Paul A. Reed is the President, Founder, and Managing Consultant of Gateway Safety Solutions, LLC — a St. Louis-based pharmacovigilance consulting firm he established in 2014. With over two decades of experience at the intersection of drug safety science, enterprise technology, and regulatory compliance, Paul brings a perspective that is genuinely rare in the industry: equal fluency in clinical pharmacology and IT systems.

A 1994 Doctor of Pharmacy graduate of St. Louis College of Pharmacy and a BS MIS graduate of Maryville University, Paul began his career in pharmaceutical drug safety at Forest Laboratories, where he spent over a decade developing deep operational expertise in ICSR processing, safety system management, and regulatory reporting — expertise that carried through the company's acquisition by Allergan. Following that tenure, he expanded into global consulting through engagements with Nextrove, Genpact, and Insife/Qinecsa, delivering pharmacovigilance system implementations and GxP validation programs for multinational pharmaceutical clients across the US and EU.

Most recently, through Gateway Safety Solutions, Paul served as Head of Client Delivery for a pharmacovigilance AI startup, leading enterprise client implementations of an NLP-powered adverse event intake platform — overseeing quality assurance, validation, and go-live delivery. He is a registered pharmacist in both Missouri and Illinois, and brings hands-on expertise across all major safety database platforms, GxP/CSV validation frameworks, ICH E2B(R2/R3) regulatory requirements, and emerging AI/ML integration in drug safety workflows.

Pharmacovigilance Drug Safety Systems GxP / 21 CFR Part 11 ICH E2B(R2/R3) AI/ML in PV Project Management Registered Pharmacist

Let's Work Together

Open to contract, FTE, and advisory engagements. Remote-friendly.

Get in Touch

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Location
St. Louis, Missouri
Remote-capable globally
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Website
gatewaysafetysolutions.com
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Engagement Types
Contract · FTE · Advisory
Project-based · Retainer
⏱️
Availability
Accepting new clients
● Available Now

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